• A Genome-Wide Association Study of a Biomarker of Nicotine Metabolism 

      Loukola, Anu; Buchwald, Jadwiga; Gupta, Richa; Palviainen, Teemu; Hällfors, Jenni; Tikkanen, Emmi; Korhonen, Tellervo; Ollikainen, Miina; Sarin, Antti-Pekka; Ripatti, Samuli; Lehtimäki, Terho; Raitakari, Olli; Salomaa, Veikko; Rose, Richard; Tyndale, Rachel; Kaprio, Jaakko (2015)
      article
      Individuals with fast nicotine metabolism typically smoke more and thus have a greater risk for smoking-induced diseases. Further, the efficacy of smoking cessation pharmacotherapy is dependent on the rate of nicotine ...
    • Gene expression profiles in Finnish twins with multiple sclerosis 

      Särkijärvi, Silja; Kuusisto, Hanna; Paalavuo, Raija; Levula, Mari; Airla, Nina; Lehtimäki, Terho; Kaprio, Jaakko; Koskenvuo, Markku; Elovaara, Irina (2006)
      article
      Background Since genetic alterations influencing susceptibility to multiple sclerosis (MS), the most common autoimmune demyelinating disease of the central nervous system (CNS), are as yet poorly understood, the purpose ...
    • Prevalence and correlates of alcohol and other substance use disorders in young adulthood: A population-based study 

      Latvala, Antti; Tuulio-Henriksson, Annamari; Perälä, Jonna; Saarni, Samuli I; Aalto-Setälä, Terhi; Aro, Hillevi; Korhonen, Tellervo; Koskinen, Seppo; Lönnqvist, Jouko; Kaprio, Jaakko; Suvisaari, Jaana (2009)
      article
      Background Several risk factors for alcohol and other substance use disorders (SUDs) have been identified, but it is not well understood whether their associations with SUD are independent of each other. In particular, ...
    • The Genetic Liability to Disability Retirement: A 30-Year Follow-Up Study of 24,000 Finnish Twins 

      Harkonmäki, Karoliina; Silventoinen, Karri; Levälahti, Esko; Pitkäniemi, Janne; Huunan-Seppälä, Antti; Klaukka, Timo; Koskenvuo, Markku; Kaprio, Jaakko (2008)
      article
      Background No previous studies on the effect of genetic factors on the liability to disability retirement have been carried out. The main aim of this study was to investigate the contribution of genetic factors on disability ...