TamPub - Selaus tekijän mukaan "Barok, Mark"
Barok, Mark; Joensuu, Heikki; Isola, Jorma (2014)
articleTrastuzumab emtansine (T-DM1) is an antibody-drug conjugate that is effective and generally well tolerated when administered as a single agent to treat advanced breast cancer. Efficacy has now been demonstrated in randomized ...
Trastuzumab-DM1 causes tumour growth inhibition by mitotic catastrophe in trastuzumab-resistant breast cancer cells in vivo Barok, Mark; Tanner, Minna; Köninki, Katri; Isola, Jorma (2011)
articleIntroduction Trastuzumab is widely used for the treatment of HER2-positive breast cancer. Despite encouraging clinical results, a significant fraction of patients are, or become, refractory to the drug. To overcome this, ...