• Effects of iron loading on muscle: genome-wide mRNA expression profiling in the mouse 

      Rodriguez, Alejandra; Hilvo, Mika; Kytömäki, Leena; Fleming, Robert E; Britton, Robert S; Bacon, Bruce R; Parkkila, Seppo (2007)
      article
      Background Hereditary hemochromatosis (HH) encompasses genetic disorders of iron overload characterized by deficient expression or function of the iron-regulatory hormone hepcidin. Mutations in 5 genes have been linked ...
    • Expression of iron-related genes in human brain and brain tumors 

      Hänninen, Milla M; Haapasalo, Joonas; Haapasalo, Hannu; Fleming, Robert E; Britton, Robert S; Bacon, Bruce R; Parkkila, Seppo (2009)
      article
      Background Defective iron homeostasis may be involved in the development of some diseases within the central nervous system. Although the expression of genes involved in normal iron balance has been intensively studied ...
    • Global Transcriptional Response to Hfe Deficiency and Dietary Iron Overload in Mouse Liver and Duodenum 

      Rodriguez, Alejandra; Luukkaala, Tiina; Fleming, Robert E; Britton, Robert S; Bacon, Bruce R; Parkkila, Seppo (2009)
      article
      Iron is an essential trace element whose absorption is usually tightly regulated in the duodenum. HFE-related hereditary hemochromatosis (HH) is characterized by abnormally low expression of the iron-regulatory hormone, ...