TamPub - Selaus tekijän mukaan "Lahti, Aleksi"
Viitteet 1-4 / 4
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Inhibition of p38 mitogen-activated protein kinase enhances c-Jun N-terminal kinase activity: Implication in inducible nitric oxide synthase expression
(2006)
articleBackground Nitric oxide (NO) is an inflammatory mediator, which acts as a cytotoxic agent and modulates immune responses and inflammation. p38 mitogen-activated protein kinase (MAPK) signal transduction pathway is activated ... -
Inhibitors of Mitogen-Activated Protein Kinases Downregulate COX-2 Expression in Human Chondrocytes
(2005)
articleInducible prostaglandin synthase (cyclooxygenase-2, COX-2) is expressed in rheumatoid and osteoarthritic cartilage and produces high amounts of proinflammatory prostanoids in the joint. In the present study we investigated ... -
Regulation of inducible nitric oxide synthase expression and nitric oxide production by mitogen-activated protein kinase pathways
Acta Electronica Universitatis Tamperensis : 384 (Tampere University Press, 2004)
VäitöskirjaNivelreuma ja astma ovat tulehdussairauksia, joissa krooninen tulehdus aiheuttaa potilaan oireet. Nivelreuman ja astman peruslääkkeet vaimentavat tulehdusreaktiota estämällä tulehduksen välittäjäaineiden tuottoa tai ... -
Tumour necrosis factor-α regulates human eosinophil apoptosis via ligation of TNF-receptor 1 and balance between NF-κB and AP-1
(2014)
articleEosinophils play a central role in asthma. The present study was performed to investigate the effect of tumour necrosis factor-α (TNF-α) on longevity of isolated human eosinophils. In contrast to Fas, TNF-α inhibited ...
