• EPHB2 germline variants in patients with colorectal cancer or hyperplastic polyposis 

      Kokko, Antti; Laiho, Päivi; Lehtonen, Rainer; Korja, Sanna (Tay); Schleutker, Johanna (Tay) (2006)
      Background Ephrin receptor B2 (EPHB2) has recently been proposed as a novel tumor suppressor gene in colorectal cancer (CRC). Inactivation of the gene has been shown to correlate with progression of colorectal tumorigenesis, ...
    • Nationwide registry-based analysis of cancer clustering detects strong familial occurrence of Kaposi sarcoma 

      Kaasinen, Eevi; Aavikko, Mervi; Vahteristo, Pia; Patama, Toni; Li, Yilong; Saarinen, Silva; Kilpivaara, Outi; Pitkänen, Esa; Knekt, Paul; Laaksonen, Maarit; Artama, Miia; Lehtonen, Rainer; Aaltonen, Lauri; Pukkala, Eero (2013)
      Many cancer predisposition syndromes are rare or have incomplete penetrance, and traditional epidemiological tools are not well suited for their detection. Here we have used an approach that employs the entire population ...