Viitteet 1-10 / 168
Long-term prognosis of breast cancer detected by mammography screening or other methods
Introduction Previous studies on breast cancer have shown that patients whose tumors are detected by mammography screening have a more favorable survival. However, little is known about the long-term prognostic impact of ...
Biological subtyping of early breast cancer: a study comparing RT-qPCR with immunohistochemistry
The biological subtype of breast cancer influences the selection of systemic therapy. Distinction between luminal A and B cancers depends on consistent assessment of Ki-67, but substantial intra-observer and inter-observer ...
Cancer incidence and cause-specific mortality in patients with metal-on-metal hip replacements in Finland
Metal-on-metal hip implants have been widely used, especially in the USA, Australia, England and Wales, and Finland. We assessed risk of death and updated data on the risk of cancer related to metal-on-metal hip ...
EPHB2 germline variants in patients with colorectal cancer or hyperplastic polyposis
Background Ephrin receptor B2 (EPHB2) has recently been proposed as a novel tumor suppressor gene in colorectal cancer (CRC). Inactivation of the gene has been shown to correlate with progression of colorectal tumorigenesis, ...
Mitä uutta eturauhassyövän molekyylibiologiassa?
Analysis of and prognostic information from disseminated tumour cells in bone marrow in primary breast cancer: a prospective observational study
Background Disseminated tumour cells (DTCs) in the bone marrow of patients with breast cancer have been identified as an independent predictor of poor prognosis in patients with non-metastatic disease. This prospective ...
Vasta-aineisiin konjugoidut solunsalpaajat tulossa syövän hoitoon
Vasta-aineisiin perustuvat lääkkeet ovat vakiinnuttaneet asemansa syövän hoidossa viimeisen vuosikymmenen aikana. Ensimmäisen sukupolven vasta-ainelääkkeiden teho perustuu niiden kykyyn tunnistaa syöpäsolu (täsmälääkeperiaate), ...