"Lahti, Aleksi" - Selaus tekijän mukaan Artikkelit
Inhibition of p38 mitogen-activated protein kinase enhances c-Jun N-terminal kinase activity: Implication in inducible nitric oxide synthase expression Lahti, Aleksi; Sareila, Outi; Kankaanranta, Hannu; Moilanen, Eeva (2006)
articleBackground Nitric oxide (NO) is an inflammatory mediator, which acts as a cytotoxic agent and modulates immune responses and inflammation. p38 mitogen-activated protein kinase (MAPK) signal transduction pathway is activated ...
Inhibitors of Mitogen-Activated Protein Kinases Downregulate COX-2 Expression in Human Chondrocytes Nieminen, Riina; Leinonen, Sari; Lahti, Aleksi; Vuolteenaho, Katriina; Jalonen, Ulla; Kankaanranta, Hannu; Goldring, Mary B; Moilanen, Eeva (2005)
articleInducible prostaglandin synthase (cyclooxygenase-2, COX-2) is expressed in rheumatoid and osteoarthritic cartilage and produces high amounts of proinflammatory prostanoids in the joint. In the present study we investigated ...
Tumour necrosis factor-α regulates human eosinophil apoptosis via ligation of TNF-receptor 1 and balance between NF-κB and AP-1 Kankaanranta, Hannu; Ilmarinen, Pinja; Zhang, Xianzhi; Adcock, Ian; Lahti, Aleksi; Barnes, Peter; Giembycz, Mark; Lindsay, Mark; Moilanen, Eeva (2014)
articleEosinophils play a central role in asthma. The present study was performed to investigate the effect of tumour necrosis factor-α (TNF-α) on longevity of isolated human eosinophils. In contrast to Fas, TNF-α inhibited ...