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The severity of Puumala hantavirus induced nephropathia epidemica can be better evaluated using plasma interleukin-6 than C-reactive protein determinations
Background Nephropathia epidemica (NE) is a Scandinavian type of hemorrhagic fever with renal syndrome caused by Puumala hantavirus. The clinical course of the disease varies greatly in severity. The aim of the present ...
Is the Prevalence of Overactive Bladder Overestimated? A Population-Based Study in Finland
Background In earlier studies, one in six adults had overactive bladder which may impair quality of life. However, earlier studies have either not been population-based or have suffered from methodological limitations. ...
Effects of a 55+ program on sickness absence in the food industry
(Tampere University Press, 2011)
Exercise training does not improve myocardial diastolic tissue velocities in Type 2 diabetes
Background Myocardial diastolic tissue velocities are reduced already in newly onset Type 2 diabetes mellitus (T2D). Poor disease control may lead to left ventricular (LV) systolic dysfunction and heart failure. The aim ...
Use of health care services and pharmaceutical agents in coeliac disease : a prospective nationwide study
Background Approximately 1% of the population suffer from coeliac disease. However, the disease is heavily underdiagnosed. Unexplained symptoms may lead to incremented medical consultations and productivity losses. The ...
Culture Conditions Affect Cardiac Differentiation Potential of Human Pluripotent Stem Cells
Human pluripotent stem cells (hPSCs), including human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs), are capable of differentiating into any cell type in the human body and thus can be used ...
Validation of morphometric analyses of small-intestinal biopsy readouts in celiac disease
Background Assessment of the gluten-induced small-intestinal mucosal injury remains the cornerstone of celiac disease diagnosis. Usually the injury is evaluated using grouped classifications (e.g. Marsh groups), but ...