Texture analysis of MR images of patients with Mild Traumatic Brain Injury

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dc.contributor.author Holli, Kirsi K -
dc.contributor.author Harrison, Lara -
dc.contributor.author Dastidar, Prasun -
dc.contributor.author Wäljas, Minna -
dc.contributor.author Liimatainen, Suvi -
dc.contributor.author Luukkaala, Tiina -
dc.contributor.author Öhman, Juha -
dc.contributor.author Soimakallio, Seppo -
dc.contributor.author Eskola, Hannu -
dc.date.accessioned 2012-06-17T20:16:30Z
dc.date.available 2012-06-16 23:44:08 -
dc.date.available 2012-06-17T20:16:30Z
dc.date.issued 2010 -
dc.identifier.issn 1471-2342 -
dc.identifier.uri http://tampub.uta.fi/handle/10024/66261
dc.description BioMed Central Open access -
dc.description.abstract Background Our objective was to study the effect of trauma on texture features in cerebral tissue in mild traumatic brain injury (MTBI). Our hypothesis was that a mild trauma may cause microstructural changes, which are not necessarily perceptible by visual inspection but could be detected with texture analysis (TA). Methods We imaged 42 MTBI patients by using 1.5 T MRI within three weeks of onset of trauma. TA was performed on the area of mesencephalon, cerebral white matter at the levels of mesencephalon, corona radiata and centrum semiovale and in different segments of corpus callosum (CC) which have been found to be sensitive to damage. The same procedure was carried out on a control group of ten healthy volunteers. Patients' TA data was compared with the TA results of the control group comparing the amount of statistically significantly differing TA parameters between the left and right sides of the cerebral tissue and comparing the most discriminative parameters. Results There were statistically significant differences especially in several co-occurrence and run-length matrix based parameters between left and right side in the area of mesencephalon, in cerebral white matter at the level of corona radiata and in the segments of CC in patients. Considerably less difference was observed in the healthy controls. Conclusions TA revealed significant changes in texture parameters of cerebral tissue between hemispheres and CC segments in TBI patients. TA may serve as a novel additional tool for detecting the conventionally invisible changes in cerebral tissue in MTBI and help the clinicians to make an early diagnosis. -
dc.language.iso en -
dc.title Texture analysis of MR images of patients with Mild Traumatic Brain Injury -
dc.type fi=Artikkeli aikakauslehdessä | en=Journal article| -
dc.identifier.urn urn:nbn:uta-3-526 -
dc.identifier.doi 10.1186/1471-2342-10-8 -
dc.type.version fi=Kustantajan versio | en=Publisher's version| -
dc.subject.okm fi=Kirurgia, anestesiologia, tehohoito, radiologia | en=Surgery, Anesthesiology, Intensive Care| -
dc.journal.title BMC Medical Imaging -
dc.journal.volume 10 -
dc.journal.number 8 -
dc.journal.volumepagerange 1-10 -
dc.oldstats 81 -

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